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glucagon receptor antagonists-1

Names

[ CAS No. ]:
503559-84-0

[ Name ]:
glucagon receptor antagonists-1

[Synonym ]:
1-(4-(2-(Benzyloxy)-4-fluorophenyl)-2,6-diisopropyl-5-(prop-1-en-1-yl)pyridin-3-yl)ethanol
4-[4-Fluoro-2-(phenylmethoxy)phenyl]-alpha-methyl-2,6-bis(1-methylethyl)-5-(1-propen-1-yl)-3-pyridinemethanol
glucagon receptor antagonists 1
glucagon receptor antagonists-1

Biological Activity

[Description]:

Glucagon receptor antagonists-1 is a highly potent glucagon receptor antagonist.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Glucagon Receptor
Research Areas >> Metabolic Disease

[References]

[1]. Ladouceur, Gaetan H. et al. Integration of optimized substituent patterns to produce highly potent 4-aryl-pyridine glucagon receptor antagonists. Bioorganic & Medicinal Chemistry Letters (2002), 12(23), 3421-3424.


[Related Small Molecules]

Exenatide acetate salt | Adomeglivant | Exendin Fragment 9-39 | MK 0893 | GLP-1(7-36) Acetate | GLP-1 (7-37) | Lixisenatide | LGD-6972 | Taspoglutide | GRA Ex-25 | GLP-1 receptor agonist 1 | GLP-1 receptor agonist-1

Chemical & Physical Properties

[ Density]:
1.094

[ Molecular Formula ]:
C29H34FNO2

[ Molecular Weight ]:
447.58400

[ Exact Mass ]:
447.25700

[ PSA ]:
42.35000

[ LogP ]:
7.79990

[ Storage condition ]:
2-8℃

Related Compounds