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m-PEG2-Tos

Names

[ CAS No. ]:
50586-80-6

[ Name ]:
m-PEG2-Tos

[Synonym ]:
diethylene glycol monomethyl ether-p-toluene sulfonate
diethyleneglycol monomethyl ether tosylate

Biological Activity

[Description]:

m-PEG2-Tos is a uncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Chemical & Physical Properties

[ Density]:
1.179±0.06 g/cm3(Predicted)

[ Boiling Point ]:
392.3±27.0 °C(Predicted)

[ Molecular Formula ]:
C12H18O5S

[ Molecular Weight ]:
292.34900

[ Exact Mass ]:
292.09800

[ PSA ]:
101.44000

[ LogP ]:
1.96420

Synthetic Route

Precursor & DownStream


Related Compounds