Pyrrolidine,1-[2-[4-[(3R,4S)-3,4-dihydro-7-methoxy-2,2-dimethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]-,rel-
Names
[ CAS No. ]:
51423-20-2
[ Name ]:
Pyrrolidine,1-[2-[4-[(3R,4S)-3,4-dihydro-7-methoxy-2,2-dimethyl-3-phenyl-2H-1-benzopyran-4-yl]phenoxy]ethyl]-,rel-
Chemical & Physical Properties
[ Density]:
1.104g/cm3
[ Boiling Point ]:
556.3ºC at 760 mmHg
[ Molecular Formula ]:
C30H35NO3
[ Molecular Weight ]:
457.60400
[ Flash Point ]:
145.6ºC
[ Exact Mass ]:
457.26200
[ PSA ]:
30.93000
[ LogP ]:
6.19440
[ Index of Refraction ]:
1.571
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UY0876400
- CHEMICAL NAME :
- Pyrrolidine, 1-(2-(4-(3,4-dihydro-7-methoxy-2,2-dimethyl-3-phenyl- 2H-1-benzopyran-4-yl) phenoxy)ethyl)-, cis-
- CAS REGISTRY NUMBER :
- 51423-20-2
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C30-H35-N-O3
- MOLECULAR WEIGHT :
- 457.66
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- IJSIDW Indian Journal of Pharmaceutical Sciences. (Kalina, Santa Cruz (East), Bombay 400 029, India) V.40(2)- 1978- Volume(issue)/page/year: 49,43,1987 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 350 mg/kg
- SEX/DURATION :
- female 1-7 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea)
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 26,592,1983
Safety Information
[ HS Code ]:
2934999090
Customs
[ HS Code ]: 2934999090
[ Summary ]:
2934999090. other heterocyclic compounds. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%