4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one
Names
[ CAS No. ]:
517-83-9
[ Name ]:
4-(1,5-dimethyl-3-oxo-2-phenyl-pyrazol-4-yl)-1,5-dimethyl-2-phenyl-pyrazol-3-one
[Synonym ]:
(4,4'-BI-3-PYRAZOLINE)-5,5'-DIONE,1,1'-DIPHENYL-2,2',3,3'-TETRAMETHYL
2,2',3,3'-Tetramethyl-1,1'-diphenyl(4,4'-bi-3-pyrazoline)-5,5'-dione
Forbisen
S. N. 475
(4,4'-Bi-1H-pyrazole)-3,3'-dione,2,2',3,3'-tetrahydro-1,1',5,5'-tetramethyl-2,2'-diphenyl
Chemical & Physical Properties
[ Density]:
1.268g/cm3
[ Boiling Point ]:
438.6ºC at 760 mmHg
[ Molecular Formula ]:
C22H22N4O2
[ Molecular Weight ]:
374.43600
[ Flash Point ]:
166.2ºC
[ Exact Mass ]:
374.17400
[ PSA ]:
53.86000
[ LogP ]:
2.94920
[ Index of Refraction ]:
1.645
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DW4000000
- CHEMICAL NAME :
- (4,4'-Bi-3-pyrazoline)-5,5'-dione, 1,1'-diphenyl-2,2',3,3'-tetramethyl-
- CAS REGISTRY NUMBER :
- 517-83-9
- BEILSTEIN REFERENCE NO. :
- 0351034
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C22-H22-N4-O2
- MOLECULAR WEIGHT :
- 374.48
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5 mg/kg
- TOXIC EFFECTS :
- Behavioral - convulsions or effect on seizure threshold
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,233,1946 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Mammal - dog
- DOSE/DURATION :
- 15 gm/kg/22W-I
- TOXIC EFFECTS :
- Behavioral - ataxia Blood - normocytic anemia Related to Chronic Data - death
- REFERENCE :
- 85GLAQ "A Survey of Antimalarial Drugs, 1941-1945," Wiselogle, F.Y., 2 vols., Ann Arbor, MI, J.W. Edwards, 1946 Volume(issue)/page/year: 1,233,1946