1,2-Dierucoyl-sn-glycero-3-PC

Names

[ Name ]:
1,2-Dierucoyl-sn-glycero-3-PC

[Synonym ]:
1,2-di-(13Z-docosenoyl)-sn-glycero-3-phosphocholine
1,2-dierucoyl-sn-glycero-3-phosphocholine
1,2-DI13-CIS-DOCOSENOYL-SN-GLYCERO-3-PHOSPHOCHOLINE

Biological Activity

[Description]:

1,2-Dierucoyl-sn-glycero-3-phosphocholine (DEPC) is the composition of liposome membrane. 1,2-Dierucoyl-sn-glycero-3-phosphocholine is used for the preparation of liposomes and studying the properties of lipid bilayers. The GO (glucose oxidase) in the 1,2-Dierucoyl-sn-glycero-3-phosphocholine liposome shows the high activity[1][2].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Masahiro INOUE, et al. Oxidation of Glucose in Gas-Liquid Flow Catalyzed by Glucose Oxidase-Containing Liposomes with Different Acyl Chain Properties. Journal of chemical engineering of japan. Published online, 2013.

[2]. Weber ME, et al. Dynamic assessment of bilayer thickness by varying phospholipid and hydraphile synthetic channel chain lengths. J Am Chem Soc. 2005 Jan 19;127(2):636-42.

Chemical & Physical Properties

[ Boiling Point ]:
480 °C

[ Molecular Formula ]:
C₅₂H₁₀₀NO₈P

[ Molecular Weight ]:
898.33

[ Exact Mass ]:
897.71900

[ PSA ]:
121.00000

[ LogP ]:
15.91520

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Bilayer Effects of Antimalarial Compounds.

PLoS ONE 10 , e0142401, (2015)

Because of the perpetual development of resistance to current therapies for malaria, the Medicines for Malaria Venture developed the Malaria Box to facilitate the drug development process. We tested t...

Whole cell screen for inhibitors of pH homeostasis in Mycobacterium tuberculosis.

PLoS ONE 8 , e68942, (2013)

Bacterial pathogens like Mycobacterium tuberculosis (Mtb) encounter acidic microenvironments in the host and must maintain their acid-base homeostasis to survive. A genetic screen identified two Mtb s...

Thiazolidinedione insulin sensitizers alter lipid bilayer properties and voltage-dependent sodium channel function: implications for drug discovery.

J. Gen. Physiol. 138(2) , 249-70, (2011)

The thiazolidinediones (TZDs) are used in the treatment of diabetes mellitus type 2. Their canonical effects are mediated by activation of the peroxisome proliferator-activated receptor γ (PPARγ) tran...