S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt

Names

[ Name ]:
S-(5′-Adenosyl)-L-methionine ptoluenesulfonate salt

[Synonym ]:
[(3S)-3-Amino-3-carboxypropyl]{[(2S,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydro-2-furanyl]methyl}methylsulfonium 4-methylbenzenesulfonate
SAM p-toluenesulfonate salt
Methionine,S-adenosyl-,DL
S-Adenosyl-DL-methionine
S-(5'-Adenosyl)-L-methionine p-toluenesulfonate salt
[(3S)-3-amino-3-carboxypropyl]-[[(2S,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methyl]-methylsulfanium,4-methylbenzenesulfonate
S-Adenosyl methionione
methyl-S-adenosyl-L-Met
S-(5′-Adenosyl)-L-methionine p-toluenesulfonate salt
AdoMet SAM p-toluenesulfonate salt

Biological Activity

[Description]:

S-Adenosyl-L-methionine tosylate is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor. S-Adenosyl-L-methionine tosylate is a dietary supplement with potent antidepressant and analgesic effects, and has the potential for liver disease and osteoarthritis research[1][2][3].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Inflammation/Immunology

Research Areas >> Neurological Disease

[Target]

Human Endogenous Metabolite

[References]

[1]. G M Bressa. et al. S-adenosyl-l-methionine (SAMe) as antidepressant: meta-analysis of clinical studies. Acta Neurol Scand Suppl. 1994;154:7-14.

[2]. Wadie I Najm, et al. S-adenosyl methionine (SAMe) versus celecoxib for the treatment of osteoarthritis symptoms: a double-blind cross-over trial. [ISRCTN36233495]. BMC Musculoskelet Disord. 2004 Feb 26;5:6.

[3]. Shelly C Lu, et al. S-adenosylmethionine in liver health, injury, and cancer. Physiol Rev. 2012 Oct;92(4):1515-42.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₃₀N₆O₈S₂

[ Molecular Weight ]:
570.639

[ Exact Mass ]:
570.156677

[ PSA ]:
273.51000

[ LogP ]:
1.33920