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Sevelamer

Names

[ CAS No. ]:
52757-95-6

[ Name ]:
Sevelamer

[Synonym ]:
poly(allylamine-co-N,N'-diallyl-1,3-diamino-2-hydroxypropane)
2-(chloromethyl)oxirane,prop-2-en-1-amine
Sevelamerum
UNII-941N5DUU5C
Sevelamero
Renagel
Renvela

Biological Activity

[Description]:

Sevelamer is a phosphate binding drug used to treat hyperphosphatemia in patients with chronic kidney disease; consists of polyallylamine that is crosslinked with epichlorohydrin.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> FXR
Research Areas >> Others

[References]

[1]. Sevelamer, From Wikipedia


[Related Small Molecules]

Obeticholic acid | GW4064 | T0901317 | Tropifexor | INT-767 | Fexaramine | Chenodeoxycholic acid | XL335 | Androsterone | PX20606 trans racemate | BAR502 | Cilofexor | LY2562175

Chemical & Physical Properties

[ Boiling Point ]:
116.1ºC at 760mmHg

[ Molecular Formula ]:
C20H46N4O

[ Molecular Weight ]:
358.61

[ Flash Point ]:
33.9ºC

[ PSA ]:
38.55000

[ LogP ]:
1.45540

[ Storage condition ]:
2-8℃

Related Compounds