Ombuin

Names

[ CAS No. ]:
529-40-8

[ Name ]:
Ombuin

[Synonym ]:
4',7-Dimethoxy-3,3',5-trihydroxyflavone
ombuine
3,5-Dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxy-4H-chromen-4-one
FLAVONE,4',7-DIMETHOXY-3,3',5-TRIHYDROXY
4',7-dimethylquercetin
4H-1-Benzopyran-4-one, 3,5-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxy-
3,5-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-7-methoxychromen-4-one
quercetin 7,4'-dimethyl ether
Flavone, 4',7-dimethoxy-3,3',5-trihydroxy-
Ombuin
7,4'-Di-O-methylquercetin
3,5,3'-trihydroxy-7,4'-dimethoxyflavone

Biological Activity

[Description]:

Ombuin, isolated from Zanthoxylum armatum, displays broad spectrum antibacterial effect with MIC ranges from 125 to 500 μg/mL[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Nooreen Z, et al. Characterization and evaluation of bioactive polyphenolic constituents from Zanthoxylum armatum DC., a traditionally used plant. Biomed Pharmacother. 2017 May;89:366-375.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
593.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₁₄O₇

[ Molecular Weight ]:
330.289

[ Flash Point ]:
222.1±23.6 °C

[ Exact Mass ]:
330.073944

[ PSA ]:
109.36000

[ LogP ]:
2.92

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.681

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LK8332000

CHEMICAL NAME :: Flavone, 4',7-dimethoxy-3,3',5-trihydroxy-

CAS REGISTRY NUMBER :: 529-40-8

BEILSTEIN REFERENCE NO. :: 0338215

LAST UPDATED :: 199612

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C17-H14-O7

MOLECULAR WEIGHT :: 330.31

WISWESSER LINE NOTATION :: T66 BOEVJ CR CQ DO1& DQ GQ IO1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 166 nmol/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 54,297,1978

Safety Information

[ HS Code ]:
2914509090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914509090

[ Summary ]:
HS:2914509090 other ketones with other oxygen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%