9H-Purine,6-(4-morpholinyl)-9-b-D-ribofuranosyl-

Names

[ Name ]:
9H-Purine,6-(4-morpholinyl)-9-b-D-ribofuranosyl-

[Synonym ]:
6-(morpholin-4-yl)-9-pentofuranosyl-9H-purine
6-morpholinopurine riboside

Biological Activity

[Description]:

6-(4-Morpholinyl)-9-β-D-ribofuranosyl-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Density]:
1.82g/cm3

[ Boiling Point ]:
684.9ºC at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₉N₅O₅

[ Molecular Weight ]:
337.33

[ Flash Point ]:
368ºC

[ Exact Mass ]:
337.13900

[ PSA ]:
125.99000

[ Index of Refraction ]:
1.805

9H-Purine,6-(4-morpholinyl)-9-b-D-ribofuranosyl-

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds