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Bromo-PEG2-C2-azide

Names

[ CAS No. ]:
530151-56-5

[ Name ]:
Bromo-PEG2-C2-azide

[Synonym ]:
1-Azido-2-[2-(2-bromoethoxy)ethoxy]ethane
Ethane, 1-(2-azidoethoxy)-2-(2-bromoethoxy)-
MFCD25424115

Biological Activity

[Description]:

Bromo-PEG2-C2-azide is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

[References]

[1]. Yong Zu Kim, et al. Antibody-drug conjugates comprising branched linkers and methods related thereto. WO2017089895A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C6H12BrN3O2

[ Molecular Weight ]:
238.082

[ Exact Mass ]:
237.011276

[ LogP ]:
0.82

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds