β-D-Fructofuranose

Names

[ Name ]:
β-D-Fructofuranose

[Synonym ]:
(2R,3S,4S,5R)-2,5-bis(hydroxymethyl)oxolane-2,3,4-triol
D(-)-Fructose
D-Fructose
β-d-Fructose
D-(-)-Fructose
Levulose
Fructose [JAN]
UNII:02T79V874P
Fructose, D-
(3S,4R,5R)-1,3,4,5,6-Pentahydroxy-2-hexanon
(3S,4R,5R)-1,3,4,5,6-Pentahydroxyhexan-2-one
Levugen
Fruit sugar
beta-D-fructofuranose
D-(-)-levulose
Fructose (JP15/USP)
b-D-Fructose
DSSTox_CID_3081
arabino-2-Hexulose
D-Levulose
(3S,4R,5R)-1,3,4,5,6-Pentahydroxy-2-hexanone
δ-Fructose
Fructooligosaccharides
Fructose
β-δ-fructose
keto-D-fructose
D-fructofuranose
β-Fruit sugar
D-arabino-Hexulose
Furucton
β-D-arabino-Hexulose
β-Levulose
Laevosan
Laevoral
Fructose, furanose form
Fructosteril

Biological Activity

[Description]:

β-D-Fructose is a β-fruit sugar that can be produced by the hydrolysis of sucrose. β-D-Fructose can be used as a sweetness potentiator. β-D-Fructose can be designed as a units of antiproliferative agents against breast (MCF-7) and colon (MDST8) cancer cell lines[1].

[Related Catalog]:

Research Areas >> Cancer

[Target]

Human Endogenous Metabolite

[References]

[1]. Carreiro EP, et al. Novel hydroxyamides and amides containing D-glucopyranose or D-fructose units: Biological assays in MCF-7 and MDST8 cell lines. Bioorg Med Chem Lett. 2016 Feb 1;26(3):1039-1043.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
551.7±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₆H₁₂O₆

[ Molecular Weight ]:
180.156

[ Flash Point ]:
301.5±26.6 °C

[ Exact Mass ]:
180.063385

[ PSA ]:
118.22000

[ LogP ]:
-1.63

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.574

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: LS7150000

CHEMICAL NAME :: beta-D-Fructose

CAS REGISTRY NUMBER :: 53188-23-1

LAST UPDATED :: 199009

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C6-H12-O6

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 14700 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PHTOEH Pharmacology and Toxicology (Copenhagen). (Munksgaard International Pub., POB 2148, DK-1016 Copenhagen K, Denmark) V.60- 1987- Volume(issue)/page/year: 64,247,1989