2-Bromothiophene-5-Sulfonamide

Names

[ Name ]:
2-Bromothiophene-5-Sulfonamide

[Synonym ]:
5-Bromothiophene-2-sulfonamide
MFCD00067990
5-Bromo-thiophene-2-sulfonic acid amide
2-Thiophenesulfonamide, 5-bromo-
5-Bromo-2-thiophenesulfonamide
2-Bromothiophene-5-Sulfonamide
2-bromo thiophene-5-sulfonamide

Chemical & Physical Properties

[ Density]:
2.0±0.1 g/cm3

[ Boiling Point ]:
386.4±52.0 °C at 760 mmHg

[ Melting Point ]:
138-142 °C(lit.)

[ Molecular Formula ]:
C₄H₄BrNO₂S₂

[ Molecular Weight ]:
242.114

[ Flash Point ]:
187.5±30.7 °C

[ Exact Mass ]:
240.886673

[ PSA ]:
96.78000

[ LogP ]:
1.03

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.647

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2935009090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2935009090

[ Summary ]:
2935009090 other sulphonamides VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:35.0%

Articles

Synthesis, Density Functional Theory (DFT), Urease Inhibition and Antimicrobial Activities of 5-Aryl Thiophenes Bearing Sulphonylacetamide Moieties.

Molecules 20 , 19914-28, (2015)

A variety of novel 5-aryl thiophenes 4a-g containing sulphonylacetamide (sulfacetamide) groups were synthesized in appreciable yields via Pd[0] Suzuki cross coupling reactions. The structures of these...

Cerebrovasodilatation through selective inhibition of the enzyme carbonic anhydrase. 3. 5-(Arylthio)-, 5-(arylsulfinyl)-, and 5-(arylsulfonyl)thiophene-2-sulfonamides.

J. Med. Chem. 24(8) , 959-64, (1981)

A series of 5-(arylthio)-, 5-(arylsulfinyl)-, and 5-(arylsulfonyl)thiophene-2-sulfonamides is described and anticonvulsant activities are listed for the compounds. In most cases, the sulfones had the ...

Acyl sulfonamide anti-proliferatives. Part 2: activity of heterocyclic sulfonamide derivatives.

Bioorg. Med. Chem. Lett. 15(3) , 617-20, (2005)

The anti-proliferative activity of acylated heterocyclic sulfonamides is described in Vascular Endothelial Growth Factor-dependent Human Umbilical Vascular Endothelial Cells (VEGF-HUVEC) and in HCT116...