Drupanin

Names

[ Name ]:
Drupanin

[Synonym ]:
(E)-3-[4-hydroxy-3-(3-methylbutenyl)phenyl]-2-propenoic acid
(E)-3-[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]acrylic acid
4-hydroxy-3-prenylcinnamic acid
3-prenyl-4-hydroxycinnamic acid
(E)-3-(4-Hydroxy-3-(3-methyl-2-butenyl)phenyl)-2-propenoic acid
2-Propenoic acid,3-(4-hydroxy-3-(3-methyl-2-butenyl)phenyl)-,(2E)
(E)-3-prenyl-p-coumaric acid
drupanin

Biological Activity

[Description]:

Drupanin is a compound isolated from green propolis. Drupanin can selectively inhibit the AKR1C3 enzyme. Drupanin has the potential for the research of breast cancer[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Rodrigues DM, et al. Synthesis, antitumor activity and in silico analyses of amino acid derivatives of artepillin C, drupanin and baccharin from green propolis. Bioorg Med Chem. 2021;47:116372.

Chemical & Physical Properties

[ Density]:
1.165g/cm3

[ Boiling Point ]:
393.3ºC at 760 mmHg

[ Molecular Formula ]:
C₁₄H₁₆O₃

[ Molecular Weight ]:
232.27500

[ Flash Point ]:
205.8ºC

[ Exact Mass ]:
232.11000

[ PSA ]:
57.53000

[ LogP ]:
2.99870

[ Index of Refraction ]:
1.608

Drupanin

Names

Biological Activity

Chemical & Physical Properties

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds