2-chloro-4h-1,3,2-benzodioxaphosphorin-4-one

Names

[ Name ]:
2-chloro-4h-1,3,2-benzodioxaphosphorin-4-one

[Synonym ]:
SalPCl Salicyl chlorophosphite
2-chloro-1,3,2-benzodioxaphosphinin-4-one
Salicylchlorophosphite
2-Chloro-4H-1,3,2-benzodioxaphosphorin-4-one
MFCD00013353

Chemical & Physical Properties

[ Boiling Point ]:
127-128 °C11 mm Hg(lit.)

[ Melting Point ]:
36-40 °C(lit.)

[ Molecular Formula ]:
C₇H₄ClO₃P

[ Molecular Weight ]:
202.53200

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
201.95900

[ PSA ]:
49.12000

[ LogP ]:
2.70150

[ Storage condition ]:
2-8°C

[ Stability ]:
Water Sensitive

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Supplemental HS ]:
Reacts violently with water.

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face particle respirator type N100 (US);Gloves;respirator cartridge type N100 (US);type P1 (EN143) respirator filter;type P3 (EN 143) respirator cartridges

[ Hazard Codes ]:
C:Corrosive;

[ Risk Phrases ]:
R14;R34

[ Safety Phrases ]:
S26-S36/37/39-S43-S45

[ RIDADR ]:
UN 3261 8/PG 1

[ WGK Germany ]:
3

[ Packaging Group ]:
II

[ Hazard Class ]:
8

[ HS Code ]:
2914700090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2914700090

[ Summary ]:
HS: 2914700090 halogenated, sulphonated, nitrated or nitrosated derivatives of ketones and quinones, whether or not with other oxygen function Tax rebate rate:9.0% Supervision conditions:none VAT:17.0% MFN tariff:5.5% General tariff:30.0%

Articles

Enzymatic primer-extension with glycerol-nucleoside triphosphates on DNA templates.

PLoS ONE 4(3) , e4949, (2009)

Glycerol nucleic acid (GNA) has an acyclic phosphoglycerol backbone repeat-unit, but forms stable duplexes based on Watson-Crick base-pairing. Because of its structural simplicity, GNA is of particula...

How to get the most out of two phosphorus chemistries. Studies on H-phosphonates.

Acc. Chem. Res. 35 , 952, (2002)

The biological importance and practical significance of phosphate esters and their analogues have been the major driving forces for research in various areas of synthetic organic phosphorus chemistry....

Byun, H.-S.; Erukulla, R. K.; Bittman, R.

J. Org. Chem. 59 , 6495, (1994)