(17β)-(2,4-2H2)Estra-1,3,5(10)-triene-3,17-diol
Names
[ CAS No. ]:
53866-33-4
[ Name ]:
(17β)-(2,4-2H2)Estra-1,3,5(10)-triene-3,17-diol
[Synonym ]:
A-Estradiol-d2
Estra-1,3,5(10)-triene-2,4-d-3,17-diol, (17β)-
(17β)-(2,4-H)Estra-1,3,5(10)-triene-3,17-diol
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
445.9±45.0 °C at 760 mmHg
[ Molecular Formula ]:
C18H22D2O2
[ Molecular Weight ]:
274.394
[ Flash Point ]:
209.6±23.3 °C
[ Exact Mass ]:
274.190186
[ PSA ]:
40.46000
[ LogP ]:
4.13
[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C
[ Index of Refraction ]:
1.599
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- KG6814500
- CHEMICAL NAME :
- Estra-1,3,5(10)-triene-2,4-D2-3,17-diol, (17-beta)-
- CAS REGISTRY NUMBER :
- 53866-33-4
- LAST UPDATED :
- 198910
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C18-H22-D2-O2
- MOLECULAR WEIGHT :
- 274.42
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Implant
- SPECIES OBSERVED :
- Rodent - hamster
- DOSE/DURATION :
- 360 mg/kg/15W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Kidney, Ureter, Bladder - Kidney tumors
- REFERENCE :
- MOPMA3 Molecular Pharmacology. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1965- Volume(issue)/page/year: 23,278,1983
Safety Information
[ Hazard Codes ]:
T: Toxic;
[ Risk Phrases ]:
R45