1-(Chloromethyl)-3-phenoxybenzene
Names
[ CAS No. ]:
53874-66-1
[ Name ]:
1-(Chloromethyl)-3-phenoxybenzene
[Synonym ]:
3-Phenoxybenzyl chloride
3-Phenoxy-1-chloromethylbenzene
3-phenoxyphenylmethyl chloride
EINECS 258-831-1
1-(Chloromethyl)-3-phenoxybenzene
MFCD00040866
3-phenyloxyphenylmethyl chloride
m-Phenoxybenzyl chloride
Chemical & Physical Properties
[ Density]:
1.189 g/mL at 25 °C(lit.)
[ Boiling Point ]:
141-142 °C(lit.)
[ Molecular Formula ]:
C13H11ClO
[ Molecular Weight ]:
218.67900
[ Flash Point ]:
>230 °F
[ Exact Mass ]:
218.05000
[ PSA ]:
9.23000
[ LogP ]:
4.21770
[ Index of Refraction ]:
n20/D 1.5900(lit.)
[ Storage condition ]:
Refrigerator (+4°C)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- CZ0790000
- CHEMICAL NAME :
- Benzene, 1-(chloromethyl)-3-phenoxy-
- CAS REGISTRY NUMBER :
- 53874-66-1
- LAST UPDATED :
- 199703
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C13-H11-Cl-O
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1224 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 56(2),16,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 5723 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(7),93,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1666 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 56(2),16,1991
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - ataxia Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 55(7),93,1990 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 4500 mg/kg/30D-I
- TOXIC EFFECTS :
- Liver - other changes Blood - leukopenia Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - true cholinesterase
- REFERENCE :
- GISAAA Gigiena i Sanitariya. For English translation, see HYSAAV. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1- 1936- Volume(issue)/page/year: 56(2),16,1991
Safety Information
[ Symbol ]:
GHS05, GHS07
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H302-H314
[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310
[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
C:Corrosive;
[ Risk Phrases ]:
R23;R24
[ Safety Phrases ]:
S26-S27-S28-S45
[ RIDADR ]:
UN 1760 8/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
CZ0790000
[ Packaging Group ]:
III
[ Hazard Class ]:
8
[ HS Code ]:
2909309090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2909309090
[ Summary ]:
2909309090 other aromatic ethers and their halogenated, sulphonated, nitrated or nitrosated derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%
Articles
Gig. Sanit. (2) , 16-9, (1991)
On the basis of experimental studies it was established, that the threshold concentration of 3-phenoxybenzyl chloride (PBC) according to the influence on organoleptic water properties (odour) is 0.03 ...