1-[(5-nitrofurfurylidene)amino]imidazolidine-2,4-dione, sodium salt

Names

[ CAS No. ]:
54-87-5

[ Name ]:
1-[(5-nitrofurfurylidene)amino]imidazolidine-2,4-dione, sodium salt

[Synonym ]:
NITROFURANTOIN SODIUM
Ivadantin
EINECS 200-216-7
Sodium nitrofurantoin
Hydantoin,1-((5-nitrofurfurylidene)amino)-,sodium salt
1-((5-Nitrofurfurylidene)amino)imidazolidine-2,4-dione,sodium salt
UNII-MAL9M0T5LV
Nitrofurandantoin sodium
Sodium furadantin

Biological Activity

[Description]:

Nitrofurantoin sodium is a potent and orally active antibacterial agent. Nitrofurantoin sodium acts as an antibiotic. Nitrofurantoin sodium can be used for the study of urinary tract infections (UTIs), including cystitis and kidney infections[1][2].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Huttner A, et al. Nitrofurantoin revisited: a systematic review and meta-analysis of controlled trials. J Antimicrob Chemother. 2015 Sep;70(9):2456-64.

[2]. Garau J. Other antimicrobials of interest in the era of extended-spectrum beta-lactamases: fosfomycin, nitrofurantoin and tigecycline. Clin Microbiol Infect. 2008 Jan;14 Suppl 1:198-202.

Chemical & Physical Properties

[ Density]:
1.81g/cm3

[ Melting Point ]:
263ºC

[ Molecular Formula ]:
C₈H₅N₄NaO₅

[ Molecular Weight ]:
260.13900

[ Exact Mass ]:
260.01600

[ PSA ]:
127.05000

[ LogP ]:
0.68300

Safety Information

[ RIDADR ]:
UN 3249

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1(b)