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Octanoyl-L-carnitine (chloride)

Names

[ CAS No. ]:
54377-02-5

[ Name ]:
Octanoyl-L-carnitine (chloride)

Biological Activity

[Description]:

L-Octanoylcarnitine hydrochloride is a plasma metabolite and a physiologically active form of octanoylcarnitine. L-Octanoylcarnitine hydrochloride can be used for the research of breast cancer[1][2][3].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

L-Octanoylcarnitine hydrochloride (0.2 mM) 诱导大鼠肝脏线粒体 (RLM) H2O2 释放[1]。

[In Vivo]

L-Octanoylcarnitine hydrochloride 碱降低高脂饮食 (HFD) 雄性小鼠的黏膜和逼尿肌的力-流呼吸，以及呼吸电导[2]。

[References]

[1]. Schönfeld P, Reiser G. Inhibition of β-oxidation is not a valid therapeutic tool for reducing oxidative stress in conditions of neurodegeneration. J Cereb Blood Flow Metab. 2017 Mar;37(3):848-854.  

[2]. Hanna Kosnik, et al. CHRONIC HIGH FAT DIET IMPAIRS DETRUSOR MITOCHONDRIAL FATTY ACID OXIDATION IN MALE BUT NOT FEMALE MICE. Journal of UrologyBladder & Urethra: Anatomy, Physiology & Pharmacology I (MP11)1 Apr 2019.

[3]. Kim M, et al. Association between arterial stiffness and serum L-octanoylcarnitine and lactosylceramide in overweight middle-aged subjects: 3-year follow-up study. PLoS One. 2015 Mar 17;10(3):e0119519.  

Chemical & Physical Properties

[ Molecular Formula ]:
C15H30ClNO4

[ Molecular Weight ]:
323.856

Related Compounds