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4-butyl-1,2-diphenylpyrazolidine-3,5-dione, compound with 4,5-dihydrothiazol-2-amine (1:1)

Names

[ CAS No. ]:
54749-86-9

[ Name ]:
4-butyl-1,2-diphenylpyrazolidine-3,5-dione, compound with 4,5-dihydrothiazol-2-amine (1:1)

[Synonym ]:
EINECS 259-319-0
4-Butyl-1,2-diphenyl-3-hydroxy-5-oxo-2-thiazolinyl-2-pyrazolidinium
2-Thiazoline-2-ammonium-4-n-butyl-1,2-diphenyl-3,5-pyrazolidinedionate
4,5-dihydro-thiazol-2-ylamine,compound with 4-butyl-1,2-diphenyl-pyrazolidine-3,5-dione (1:1)
4-Butyl-1,2-diphenylpyrazolidine-3,5-dione,compound with 4,5-dihydrothiazol-2-amine (1:1)
Thiazolinobutazone
Phenylbutazone salt with 2-amino-2-thiazoline
3,5-Pyrazolidinedione,4-butyl-1,2-diphenyl-,salt with 2-amino-2-thiazoline
Fordonal
compound with 4,5-dihydrothiazol-2-amine (1:1)

Chemical & Physical Properties

[ Boiling Point ]:
424.9ºC at 760 mmHg

[ Molecular Formula ]:
C22H26N4O2S

[ Molecular Weight ]:
410.53200

[ Flash Point ]:
174.3ºC

[ Exact Mass ]:
410.17800

[ PSA ]:
101.80000

[ LogP ]:
4.60390

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UQ8250000
CHEMICAL NAME :
3,5-Pyrazolidinedione, 4-butyl-1,2-diphenyl-, salt with 2-amino-2-thiazoline
CAS REGISTRY NUMBER :
54749-86-9
LAST UPDATED :
197910
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C22-H24-N3-O2-S
MOLECULAR WEIGHT :
394.55
WISWESSER LINE NOTATION :
T5VNNV EHJ BR& CR& E4 &T5N CS AUTJ BZ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1425 mg/kg
TOXIC EFFECTS :
Gastrointestinal - ulceration or bleeding from stomach
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,1347,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
1650 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,1347,1976
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
338 mg/kg
TOXIC EFFECTS :
Behavioral - changes in motor activity (specific assay)
REFERENCE :
ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 26,1347,1976

Synthetic Route

Precursor & DownStream


Related Compounds