2-(3,3-diphenylpropyl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine
Names
[ CAS No. ]:
55011-89-7
[ Name ]:
2-(3,3-diphenylpropyl)-1,3,4,6,7,8,9,9a-octahydropyrido[1,2-a]pyrazine
[Synonym ]:
Octahydro-2-(3,3-diphenylpropyl)-2H-pyrido(1,2-a)pyrazine
2-(3,3-diphenylpropyl)octahydro-2h-pyrido[1,2-a]pyrazine
2H-Pyrido(1,2-a)pyrazine,octahydro-2-(3,3-diphenylpropyl)
N,N,1-Trimethyl-3,3-diphenylallylamine Hydrochloride
Chemical & Physical Properties
[ Molecular Formula ]:
C23H30N2
[ Molecular Weight ]:
334.49800
[ Exact Mass ]:
334.24100
[ PSA ]:
6.48000
[ LogP ]:
4.25450
Safety Information
[ Symbol ]:
GHS06
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H301
[ Precautionary Statements ]:
P301 + P310
[ Hazard Codes ]:
T
[ Risk Phrases ]:
25
[ Safety Phrases ]:
45
[ RIDADR ]:
UN 2811 6.1 / PGIII
Articles
Eur. J. Clin. Pharmacol. 19(3) , 217-23, (1981)
The pharmacokinetic constants and rectal bioavailability of the narcotic analgesic ketobemidone were determined in six male patients after surgery. Plasma concentrations were measured following intrav...
The mu1 and mu2 opioid receptor binding of ketobemidone, norketobemidone and 3-dimethylamino-1,1-diphenylbutene.Pharmacol. Toxicol. 79(2) , 103-4, (1996)
Ketobemidone plus (RS)-3-dimethylamino-1,1-diphenylbut-1-ene (A29) is more potent at NMDA receptors than ketobemidone alone: evidence for A29 as a non-competitive NMDA receptor antagonist.
Pharmacol. Toxicol. 82(3) , 157-60, (1998)
The opioid, ketobemidone, has previously been shown to be a non-competitive N-methyl-D-aspartate (NMDA) receptor antagonist. In Denmark, ketobemidone is available in a formulation which contains ketob...