N,N-dinitrosohomopiperazine

Names

[ Name ]:
N,N-dinitrosohomopiperazine

[Synonym ]:
Dinitrosohomopiperazine
LS-7359
1H-1,4-DIAZEPINE,HEXAHYDRO-1,4-DINITROSO
N,N-Dinitrosohomopiperazine
N,N'-Dinitroso-homopiperazin

Chemical & Physical Properties

[ Density]:
1.43g/cm3

[ Boiling Point ]:
403.1ºC at 760 mmHg

[ Molecular Formula ]:
C₅H₁₀N₄O₂

[ Molecular Weight ]:
158.15800

[ Flash Point ]:
197.6ºC

[ Exact Mass ]:
158.08000

[ PSA ]:
65.34000

[ LogP ]:
0.23270

[ Index of Refraction ]:
1.622

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: HM3950000

CHEMICAL NAME :: 1H-1,4-Diazepine, hexahydro-1,4-dinitroso-

CAS REGISTRY NUMBER :: 55557-00-1

BEILSTEIN REFERENCE NO. :: 0147155

LAST UPDATED :: 199710

DATA ITEMS CITED :: 9

MOLECULAR FORMULA :: C5-H10-N4-O2

MOLECULAR WEIGHT :: 158.19

WISWESSER LINE NOTATION :: T7N DNTJ ANO DNO

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 65 mg/kg/2Y-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors Liver - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 105 mg/kg/30W-I

TOXIC EFFECTS :: Tumorigenic - Carcinogenic by RTECS criteria Gastrointestinal - tumors

TYPE OF TEST :: TD - Toxic dose (other than lowest)

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 1530 mg/kg/31W-I

TOXIC EFFECTS :: Tumorigenic - equivocal tumorigenic agent by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Gastrointestinal - tumors

MUTATION DATA

TYPE OF TEST :: Mutation in mammalian somatic cells

TEST SYSTEM :: Rodent - hamster Ovary

DOSE/DURATION :: 5 umol/L

REFERENCE :: TCMUE9 Topics in Chemical Mutagenesis. (Plenum Pub. Corp., 233 Spring Street, New York, NY 10013) V.1- 1984- Volume(issue)/page/year: 1,129,1984