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Macitentan n-butyl analogue

Names

[ CAS No. ]:
556797-16-1

[ Name ]:
Macitentan n-butyl analogue

[Synonym ]:
Macitentan (n-butyl analogue)

Biological Activity

[Description]:

Macitentan n-butyl analogue is a n-butyl analogue of Macitentan. Macitentan is an orally active, non-peptide dual endothelin ETA and ETB receptor antagonist for the potential treatment of idiopathic pulmonary fibrosis (IPF) and pulmonary arterial hypertension (PAH).

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Endothelin Receptor
Research Areas >> Cardiovascular Disease

[Related Small Molecules]

BQ-788 (sodium salt) | Endothelin-1 (human, bovine, dog, mouse, porcine, rat) acetate salt | Atrasentan hydrochloride | BQ-123 | Zibotentan (ZD4054) | ACT-132577 | RE 201 | Atrial Natriuretic Factor (1-28) (mouse, rabbit, rat) trifluoroacetate salt | Avosentan | Sitaxentan sodium | IRL-1620 TFA | Sulfisoxazole | Aminaftone | PD-159020 | Ro 46-2005

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
687.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C20H21Br2N5O4S

[ Molecular Weight ]:
587.285

[ Flash Point ]:
369.5±34.3 °C

[ Exact Mass ]:
584.968079

[ LogP ]:
5.91

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.623

[ Storage condition ]:
2-8℃

Related Compounds