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Leiophrrole

Names

[ CAS No. ]:
5633-16-9

[ Name ]:
Leiophrrole

[Synonym ]:
1-[2-(2-Diaethylamino-aethoxy)-phenyl]-2-methyl-5-phenyl-pyrrol
1-(2-<2-Diethylamino-ethoxy>-phenyl)-2-methyl-5-phenyl-pyrrol
Leiopyrrole
Pyrrole,1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-phenyl
Leiopirrol [INN-Spanish]
Ethanamine,N,N-diethyl-2-(2-(2-methyl-5-phenyl-1H-pyrrol-1-yl)phenoxy)
Leiopirrol
Leiopyrrolum [INN-Latin]
1-(o-(2-(Diethylamino)ethoxy)phenyl)-2-methyl-5-phenylpyrrole
2-Methyl-5-phenyl-1-<2-(2-diethylamino-ethoxy)-phenyl>-pyrrol
1-[2-(2-diethylamino-ethoxy)-phenyl]-2-methyl-5-phenyl-pyrrole
DV 714
Leioplegil

Chemical & Physical Properties

[ Density]:
1.01g/cm3

[ Boiling Point ]:
497.9ºC at 760mmHg

[ Molecular Formula ]:
C23H28N2O

[ Molecular Weight ]:
348.48100

[ Flash Point ]:
254.9ºC

[ Exact Mass ]:
348.22000

[ PSA ]:
17.40000

[ LogP ]:
5.17330

[ Index of Refraction ]:
1.552

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
UX9465050
CHEMICAL NAME :
Pyrrole, 1-(o-(2-(diethylamino)ethoxy)phenyl)-2-methyl-5-pheny l-
CAS REGISTRY NUMBER :
5633-16-9
BEILSTEIN REFERENCE NO. :
0300657
LAST UPDATED :
199612
DATA ITEMS CITED :
4
MOLECULAR FORMULA :
C23-H28-N2-O
MOLECULAR WEIGHT :
348.53

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
700 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 20,371,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 20,371,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
475 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 20,371,1963
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
115 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
AAREAV Anesthesie, Analgesie, Reanimation. (Paris, France) V.14-38, 1957-81. Volume(issue)/page/year: 20,371,1963

Synthetic Route

Precursor & DownStream