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NOTA

Names

[ CAS No. ]:
56491-86-2

[ Name ]:
NOTA

[Synonym ]:
1H-1,4,7-Triazonine-1,4,7-triacetic acid,hexahydro
NOTA
1,4,7-triazacyclononane-1,4,7-triacetic acid
1,4,7-triazacyclononane-N,N',N''-triacetic acid
67Ga-9N3

Biological Activity

[Description]:

NOTA is a bifunctional chelate which acts as the framework to construct PET imaging tools. NOTA also can be used for probe design and signal amplification via the multivalent effect[1][2].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Singh AN, et al. Multivalent bifunctional chelator scaffolds for gallium-68 based positron emission tomography imaging probe design: signal amplification via multivalency. Bioconjug Chem. 2011;22(8):1650-1662.

[2]. Liao AH, et al. Evaluation of 18F-labeled targeted perfluorocarbon-filled albumin microbubbles as a probe for microUS and microPET in tumor-bearing mice. Ultrasonics. 2013;53(2):320-327.

Chemical & Physical Properties

[ Density]:
1.321g/cm3

[ Boiling Point ]:
572.9ºC at 760 mmHg

[ Molecular Formula ]:
C12H21N3O6

[ Molecular Weight ]:
303.31200

[ Flash Point ]:
300.3ºC

[ Exact Mass ]:
303.14300

[ PSA ]:
121.62000

[ Index of Refraction ]:
1.531

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds