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(2S)-2-amino-3-disulfanyl-propanoic acid

Names

[ CAS No. ]:
5652-32-4

[ Name ]:
(2S)-2-amino-3-disulfanyl-propanoic acid

[Synonym ]:
cysteine persulfide
S-sulfanylcysteine
(2R)-2-amino-3-(disulfanyl)propanoic acid
CSS
3-(thiosulfeno)-alanine
S-MERCAPTOCYSTEINE
s-thiocystine
cysteine perthiol
Thiocysteine

Biological Activity

[Description]:

Thiocystine is the trisulfide analog of cysteine, it can modify cysteine in proteins. Thiocystine is an activator for aminolevulinate synthetase. Thiocystine can be used for cysteine metabolism research[1][2].

[Related Catalog]:

Research Areas >> Others

[In Vitro]

Thiocysteine 可直接与活性氧相互作用[2]。

[In Vivo]

Thiocystine (120 mg/kg；静脉注射，一次) 具有对抗氰化物毒性的保护特性[1]。 Animal Model: Adult male and female rats with cyanide injection[1] Dosage: 120 mg/kg Administration: Intravenous injection; 120 mg/kg, once Result: Showed completely protective effects to testing animals.

[References]

[1]. Wood JL. Nutritional and protective properties of thiocystine. Proc Soc Exp Biol Med. 1980 Dec;165(3):469-72.  

[2]. Reitzer L. Death by Cystine: an Adverse Emergent Property from a Beneficial Series of Reactions. J Bacteriol. 2015 Dec;197(23):3626-8.  

Chemical & Physical Properties

[ Molecular Formula ]:
C3H7NO2S2

[ Molecular Weight ]:
153.22300

[ Exact Mass ]:
152.99200

[ PSA ]:
127.42000

[ LogP ]:
0.67660

Related Compounds