3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine

Names

[ Name ]:
3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine

[Synonym ]:
3'',5''-diacetyl-5-iodo-2''-fluoro-2''-deoxyuridine

Biological Activity

[Description]:

3’,5’-Di-O-acetyl-2’-deoxy-2’-fluoro-5-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₃H₁₄FIN₂O₇

[ Molecular Weight ]:
456.16

[ Exact Mass ]:
455.98300

[ PSA ]:
116.69000

3',5'-Di-O-acetyl-2'-deoxy-2'-fluoro-5-iodouridine

Names

Biological Activity

Chemical & Physical Properties

Related Compounds