Therafectin

Names

[ Name ]:
Therafectin

[Synonym ]:
1,2-O-Isopropylidene-3-O-[3-(N,N-dimethylamino)propyl]-a-D-glucofuranose
SM-1213

Biological Activity

[Description]:

Amiprilose (SM1213; Therafectin) is a potent inhibitor against Hepatocellular carcinoma (HCC). Amiprilose induces lymphokine-induced macrophage activation directly to kill Listeria monocytogenes[1][2].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Bacterial

[References]

[1]. Wang XK, et al. Clinical significance of long non-coding RNA DUXAP8 and its protein coding genes in hepatocellular carcinoma. J Cancer. 2020 Aug 25;11(20):6140-6156.

[2]. Hadden JW. Effects of isoprinosine, levamisole, muramyl dipeptide, and SM1213 on lymphocyte and macrophage function in vitro. Cancer Treat Rep. 1978 Nov;62(11):1981-5.

Chemical & Physical Properties

[ Density]:
1.21g/cm3

[ Boiling Point ]:
431ºC at 760mmHg

[ Melting Point ]:
255ºC

[ Molecular Formula ]:
C₁₄H₂₈ClNO₆

[ Molecular Weight ]:
341.82800

[ Flash Point ]:
214.5ºC

[ Exact Mass ]:
341.16100

[ PSA ]:
80.62000

[ LogP ]:
0.35490

[ Index of Refraction ]:
1.521

[ Storage condition ]:
-20°C

Safety Information

[ Risk Phrases ]:
R23/24/25

[ Safety Phrases ]:
22-26-36-45

Therafectin

Names

Biological Activity

Chemical & Physical Properties

Safety Information

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds