(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1)
Names
[ CAS No. ]:
5685-86-9
[ Name ]:
(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1)
[Synonym ]:
1-METHYL-2-[2-(2-THIENYL)ETHENYL]-1,4,5,6-TETRAHYDROPYRIMIDINE CITRATE SALT
1-methyl-2-(2-[2-thienyl]ethenyl)-1,4,5,6-tetrahydropyrimidine
(E)-1,4,5,6-tetrahydro-1-methyl-2-[2-(2-thienyl)vinyl]pyrimidine citrate (1:1)
Chemical & Physical Properties
[ Boiling Point ]:
324.4ºC at 760 mmHg
[ Molecular Formula ]:
C17H22N2O7S
[ Molecular Weight ]:
398.43100
[ Flash Point ]:
150ºC
[ Exact Mass ]:
398.11500
[ PSA ]:
175.97000
[ LogP ]:
0.62030
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P301 + P312 + P330-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;Gloves;type P2 (EN 143) respirator cartridges
[ Hazard Codes ]:
T: Toxic;
[ Risk Phrases ]:
23/24/25-36
[ Safety Phrases ]:
26-36/37/39-45
[ RIDADR ]:
NONH for all modes of transport
Articles
Antimicrob. Agents Chemother. 52 , 3980-3986, (2008)
The anthelmintic pyrantel plays an important role in the control of gastrointestinal helminths of humans and domestic animals. Despite the demonstration of pyrantel resistance in several helminth spec...
Paraherquamide and 2-deoxy-paraherquamide distinguish cholinergic receptor subtypes in Ascaris muscle.J. Pharmacol. Exp. Ther. 302 , 853, (2002)
Paraherquamide is a novel natural anthelmintic product with a mode of action that is incompletely characterized. Nicotine and cholinergic-anthelmintic agonists of different chemical classes were used ...
The mechanism of the paralysing action of tetramisole on Ascaris somatic muscle.Br. J. Pharmacol. 38 , 602-607, (1970)
1. Tetramisole (100 mug/ml) paralysed live Ascaris in 3 min.2. Tetramisole (10 mug/ml) caused a sustained contraction of the isolated somatic muscles of the worm. This contraction was not blocked by c...