n-(tert-butyl)hydroxylamine hydrochloride

Names

[ Name ]:
n-(tert-butyl)hydroxylamine hydrochloride

[Synonym ]:
N-Hydroxy-2-methylpropan-2-amine hydrochloride (1:1)
N-tert-butylhydroxylamine,hydrochloride
2-Propanamine, N-hydroxy-2-methyl-, hydrochloride (1:1)
N-Hydroxy-2-methyl-2-propanamine hydrochloride (1:1)
MFCD00012598
EINECS 260-771-6

Chemical & Physical Properties

[ Density]:
0.883g/cm3

[ Boiling Point ]:
120.9ºC at 760mmHg

[ Melting Point ]:
183-185 °C(lit.)

[ Molecular Formula ]:
C₄H₁₂ClNO

[ Molecular Weight ]:
125.597

[ Flash Point ]:
43.6ºC

[ Exact Mass ]:
125.060745

[ PSA ]:
32.26000

[ LogP ]:
1.95660

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S22-S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2928000090

Customs

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

Articles

N-t-Butyl hydroxylamine is an antioxidant that reverses age-related changes in mitochondria in vivo and in vitro.

FASEB J. 15(12) , 2196-204, (2001)

N-t-butyl hydroxylamine (NtBHA) delays senescence-dependent changes in human lung fibroblasts (IMR90) (Atamna et al., J. Biol. Chem. 275, 6741-6748). The current study examines the effect of NtBHA on ...

Developmental differences in the immortalization of lung fibroblasts by telomerase.

Aging Cell 2(5) , 235-43, (2003)

The role of ambient (21%) and physiological oxygen (2-5%) in the immortalization of fetal vs. adult human lung fibroblasts was examined. Growth in low oxygen and antioxidants extended the lifespan of ...

A New Three-Component Cascade Reaction to Yield 3-Spirocyclopropanatedß-Lactams. Zanobini A, et al.

European J. Org. Chem. 2006(5) , 1251-55, (2006)