Antibiotic C 9154
Names
Biological Activity
[Description]:
Fumaramidmycin is an antibiotic found in Streptomyces kurssanovii NR-7GG1. Fumaramidmycin shows an antimicrobial activity against both Gram-positive and Gram-negative bacteria[1].
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Density]:
1.25g/cm3
[ Boiling Point ]:
510.8ºC at 760 mmHg
[ Molecular Formula ]:
C12H12N2O3
[ Molecular Weight ]:
232.23500
[ Flash Point ]:
262.7ºC
[ Exact Mass ]:
232.08500
[ PSA ]:
89.26000
[ LogP ]:
1.00460
[ Index of Refraction ]:
1.577
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- EM4300000
- CHEMICAL NAME :
- 2-Butenediamide, N-(phenylacetyl)-, (E)-
- CAS REGISTRY NUMBER :
- 57687-92-0
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C12-H12-N2-O3
- MOLECULAR WEIGHT :
- 232.26
- WISWESSER LINE NOTATION :
- ZV1U1VMV1R
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 1250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- JANTAJ Journal of Antibiotics. (Japan Antibiotics Research Assoc., 2-20-8 Kamiosaki, Shinagawa-ku, Tokyo, 141, Japan) V.2-5, 1948-52; V.21- 1968- Volume(issue)/page/year: 28,636,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- 85ERAY "Antibiotics: Origin, Nature, and Properties," Korzyoski, T., et al., eds., Washington, DC, American Soc. for Microbiology, 1978 Volume(issue)/page/year: 1,759,1978