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Acetyl-α-MSH (11-13) hydrochloride salt

Names

[ CAS No. ]:
57899-96-4

[ Name ]:
Acetyl-α-MSH (11-13) hydrochloride salt

[Synonym ]:
Ac-Lys-pro-valnh2
N-Acetyl-L-lysyl-L-prolyl-L-valinamide
L-Valinamide, N-acetyl-L-lysyl-L-prolyl-
N-Acetyllysyl-prolyl-valinamide
1-Valinamide,N2-acetyl-L-lysyl-L-propyl

Biological Activity

[Description]:

Acetyl-α-MSH (11-13) is the acetylated C-terminal tripeptide of α-MSH with antipyretic and anti-inflammatory activities[1][2].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Schiöth HB, et al. New melanocortin 1 receptor binding motif based on the C-terminal sequence of alpha-melanocyte-stimulating hormone. Basic Clin Pharmacol Toxicol. 2006 Oct;99(4):287-93.  

[2]. Shimizu H, et al. Alpha-melanocyte-stimulating hormone (MSH) inhibits insulin secretion in HIT-T 15 cells. Peptides. 1995;16(4):605-8.Shimizu H, et al. Alpha-melanocyte-stimulating hormone (MSH) inhibits insulin secretion in HIT-T 15 cells. Peptides. 1995;16(4):605-8.  

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
743.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C18H33N5O4

[ Molecular Weight ]:
383.49

[ Flash Point ]:
403.7±32.9 °C

[ Exact Mass ]:
383.253265

[ PSA ]:
147.62000

[ LogP ]:
-1.17

[ Vapour Pressure ]:
0.0±2.5 mmHg at 25°C

[ Index of Refraction ]:
1.528

Related Compounds