2′,5′-Dideoxy-5′-iodouridine

Names

[ Name ]:
2′,5′-Dideoxy-5′-iodouridine

[Synonym ]:
Uridine,2',5'-dideoxy-5'-iodo

Biological Activity

[Description]:

2′,5′-Dideoxy-5′-iodouridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.

Chemical & Physical Properties

[ Molecular Formula ]:
C₉H₁₁IN₂O₄

[ Molecular Weight ]:
338.10

[ Exact Mass ]:
337.97600

[ PSA ]:
84.58000

[ LogP ]:
0.03230

2′,5′-Dideoxy-5′-iodouridine

Names

Biological Activity

Chemical & Physical Properties

Precursor & DownStream

Precursor

DownStream

Related Compounds