MBS Crosslinker

Names

[ Name ]:
MBS Crosslinker

[Synonym ]:
Succinimidylmaleimidobenzoate
Einecs 261-368-8
m-maleimimidobenzoyl-N-hydroxysuccinamide ester
3-MaleiMidobenzoic acid-NHS ester
3-maleimidobenzoyl N-hydroxysuccinimide ester
1-(3-{[(2,5-Dioxo-1-pyrrolidinyl)oxy]carbonyl}phenyl)-1H-pyrrole-2,5-dione
1-(3-{[(2,5-Dioxopyrrolidin-1-yl)oxy]carbonyl}phenyl)-1H-pyrrole-2,5-dione
3-N-Maleimidobenzoic acid-NHS
N-hydroxysuccimidyloxy m-maleimidobenzoate
1H-Pyrrole-2,5-dione, 1-[3-[[(2,5-dioxo-1-pyrrolidinyl)oxy]carbonyl]phenyl]-
m-maleimidobenzoyl-N-hydroxysuccinimide ester
N-SUCCINIMIDYL 3-MALEIMIDOBENZOATE
3-Maleimido-benzoic acid-OSu
1-(3-(((2,5-Dioxopyrrolidinyl)oxy)carbonyl)phenyl)-1H-pyrrole-2,5-dione
MFCD00005514
M-N-MALEIMIDOBENZOIC ACID-OSU
m-maleimidobenzoic acid succinimido ester
MBS

Biological Activity

[Description]:

3-Maleimidobenzoic acid N-hydroxysuccinimide ester is used as asymmetric spacers[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. N. V. Komarova, et al. Optimization of silicon dioxide surface functionalization protocol for designing the receptor layer of a biosensor for detecting explosives. Moscow University Chemistry Bulletin volume 71, pages 25-31 (2016).

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
524.5±52.0 °C at 760 mmHg

[ Melting Point ]:
175-177 °C(lit.)

[ Molecular Formula ]:
C₁₅H₁₀N₂O₆

[ Molecular Weight ]:
314.250

[ Flash Point ]:
271.0±30.7 °C

[ Exact Mass ]:
314.053894

[ PSA ]:
101.06000

[ LogP ]:
-1.18

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.678

[ Storage condition ]:
−20°C

[ Water Solubility ]:
ethyl acetate or DMF: ≤20 mg/mL may require addition of solvent to coupling buffer to at least 5% to maintain solubility

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Assembly of Slx4 signaling complexes behind DNA replication forks.

EMBO J. 34 , 2182-97, (2015)

Obstructions to replication fork progression, referred to collectively as DNA replication stress, challenge genome stability. In Saccharomyces cerevisiae, cells lacking RTT107 or SLX4 show genome inst...

The Cell Adhesion Molecule Necl-4/CADM4 Serves as a Novel Regulator for Contact Inhibition of Cell Movement and Proliferation.

PLoS ONE 10(4) , e0124259, (2015)

Contact inhibition of cell movement and proliferation is critical for proper organogenesis and tissue remodeling. We show here a novel regulatory mechanism for this contact inhibition using cultured v...

The impact of carbon nanomaterials on the development of phenanthrene catabolism in soil.

Environ. Sci. Process. Impacts 17 , 1302-10, (2015)

This study investigates the impact of different types of carbon nanomaterials (CNMs) namely C60, multi-walled carbon nanotubes (MWCNTs) and fullerene soot on the catabolism of (14)C-phenanthrene in so...