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3-O-Methyldopa D3

Names

[ CAS No. ]:
586954-09-8

[ Name ]:
3-O-Methyldopa D3

Biological Activity

[Description]:

3-O-Methyldopa D3 (3-Methoxy-L-tyrosine D3) is deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa competitively inhibits the pharmacodynamics of l-DOPA and dopamine[1].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Dopamine Receptor
Signaling Pathways >> Neuronal Signaling >> Dopamine Receptor
Research Areas >> Neurological Disease

[References]

[1]. Masato Asanuma, et al. 3-O-Methyldopa inhibits astrocyte-mediated dopaminergic neuroprotective effects of L-DOPA. BMC Neurosci. 2016 Jul 25;17(1):52.

Chemical & Physical Properties

[ Molecular Formula ]:
C10H10D3NO4

[ Molecular Weight ]:
214.23300

[ Exact Mass ]:
214.10300

[ PSA ]:
92.78000

[ LogP ]:
1.05550

Related Compounds