D-Cyclohexylalanine

Names

[ Name ]:
D-Cyclohexylalanine

[Synonym ]:
(R)-(+)-α-Aminocyclohexanepropionic acid
L6TJ A1YZVQ &&D or R Form
(αR)-α-Aminocyclohexanepropionic acid
3-Cyclohexyl-D-alanine
(αR)-α-Aminocyclohexanepropanoic acid
Cyclohexanepropanoic acid, α-amino-, (αR)-
h-d-cha-oh
(R)-α-Aminocyclohexanepropionic acid
MFCD00153485
(R)-3-Cyclohexylalanine
D-Cyclohexylalanine

Biological Activity

[Description]:

(R)-2-amino-3-cyclohexylpropanoic acid is an alanine derivative[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[In Vitro]

Amino acids and amino acid derivatives have been commercially used as ergogenic supplements. They influence the secretion of anabolic hormones, supply of fuel during exercise, mental performance during stress related tasks and prevent exercise induced muscle damage. They are recognized to be beneficial as ergogenic dietary substances[1].

[References]

[1]. Luckose F, et al. Effects of amino acid derivatives on physical, mental, and physiological activities. Crit Rev Food Sci Nutr. 2015;55(13):1793-1036.

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
307.1±25.0 °C at 760 mmHg

[ Molecular Formula ]:
C₉H₁₇NO₂

[ Molecular Weight ]:
171.237

[ Flash Point ]:
139.6±23.2 °C

[ Exact Mass ]:
171.125931

[ PSA ]:
63.32000

[ LogP ]:
1.91

[ Vapour Pressure ]:
0.0±1.4 mmHg at 25°C

[ Index of Refraction ]:
1.498

[ Storage condition ]:
Store at 0°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
22

[ Safety Phrases ]:
22-24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2922499990

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2922499990

[ Summary ]:
HS:2922499990 other amino-acids, other than those containing more than one kind of oxygen function, and their esters; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) MFN tariff:6.5% General tariff:30.0%

Articles

Experimental evaluation of CH-π interactions in a protein core.

Chemistry 18(19) , 5832-6, (2012)

CH-π stacks up! Using the protein α(2) D as a model system, we estimate that a CH-π contact between cyclohexylalanine (Cha) and phenylalanine (F) contributes approximately -0.7 kcal mol(-1) to the pr...

Sequential and specific exchange of multiple coiled-coil components.

J. Am. Chem. Soc. 125(43) , 13046-51, (2003)

The capacity for sequential and specific exchange of single peptides from coiled-coil heterotrimers is investigated. Dual hydrophobic-hydrophilic interface systems permit iterative cycles of pH-trigge...

Mapping the ligand-binding site on the C5a receptor: arginine74 of C5a contacts aspartate282 of the C5a receptor.

Biochemistry 40(46) , 14047-52, (2001)

The interaction between the anaphylatoxin C5a and its receptor involves two distinct sites. One site is formed by acidic residues at the receptor N-terminus and contributes to only ligand binding. The...