A2315A

Names

[ CAS No. ]:
58717-24-1

[ Name ]:
A2315A

[Synonym ]:
Antibiotic A 2315A
Madumycin II
A2315A
A-2315
Antibiotic A 2315
Madumicin II

Biological Activity

[Description]:

A2315A (Madumycin II) is an alanine-containing streptogramin A antibiotic. A2315A is a potent peptidyl transferase center (PTC) inhibitor. A2315A inhibits the ribosome prior to the first cycle of peptide bond formation[1].

[Related Catalog]:

Research Areas >> Infection

[References]

[1]. Osterman IA, et, al. Madumycin II inhibits peptide bond formation by forcing the peptidyl transferase center into an inactive state. Nucleic Acids Res. 2017 Jul 7;45(12):7507-7514.  

Chemical & Physical Properties

[ Molecular Formula ]:
C26H37N3O7

[ Molecular Weight ]:
503.58800

[ Exact Mass ]:
503.26300

[ PSA ]:
157.97000

[ LogP ]:
2.12600

Related Compounds