DL-Glyceraldehyde 3-phosphate

[Description]:

DL-Glyceraldehyde 3-phosphate is an intermediate in several metabolic pathways, including glycolysis and gluconeogenesis. DL-Glyceraldehyde 3-phosphate is a potent inhibitor of the growth of E. coli. DL-Glyceraldehyde 3-phosphate is a competitive inhibitor of the acyltransferase[1][2].

[Related Catalog]:

Research Areas >> Infection

Research Areas >> Metabolic Disease

Signaling Pathways >> Anti-infection >> Bacterial

[In Vitro]

DL-Glyceraldehyde 3-phosphate is a time-dependent inhibitor of the cationic and anionic isozymes of aspartate aminotransferase purified from rat liver[1]. DL-Glyceraldehyde 3-phosphate, an analogue of Glycerol 3-phosphate, enters the cell via the sn-glycerol 3-phosphate transport system and is bactericidal. DL-Glyceraldehyde 3-phosphate is an inhibitor of sn-glycerol 3-phosphate transport[2].

[In Vivo]

In vivo, phosphatidylethanolamine and phosphatidylglycerol accumulation are inhibited to the same extent by the addition of DL-Glyceraldehyde 3-phosphate to a culture of E. coli[2].

[References]

[1]. L Kopelovich, et al. Kinetics of the inhibition of aspartate aminotransferase isozymes by DL-glyceraldehyde 3-phosphate. Eur J Biochem. 1971 Jun 11;20(3):351-62.

[2]. C T Tang, et al. L-Glyceraldehude 3-phosphate, a bactericidal agent. Antimicrob Agents Chemother. 1977 Jan;11(1):147-53.

[ Density]:
1.721g/cm3

[ Boiling Point ]:
399.2ºC at 760mmHg

[ Molecular Formula ]:
C₃H₇O₆P

[ Molecular Weight ]:
170.05800

[ Flash Point ]:
195.2ºC

[ Exact Mass ]:
169.99800

[ PSA ]:
113.87000

Click to get detail MSDS

[ Symbol ]:

GHS05

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H314

[ Precautionary Statements ]:
P280-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Risk Phrases ]:
34

[ Safety Phrases ]:
26-27-36/37/39-45

[ RIDADR ]:
UN 1760 8/PG 2

[ Packaging Group ]:
II

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