1-Oleoyl-2-palmitoyl-sn-glycero-3-PC

Names

[ Name ]:
1-Oleoyl-2-palmitoyl-sn-glycero-3-PC

[Synonym ]:
1-Oleoyl-2-palmitoyl-sn-glycero-3-phosphocholine
(2R)-3-[(9Z)-9-Octadecenoyloxy]-2-(palmitoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
Ethanaminium, 2-[[hydroxy[(2R)-2-[(1-oxohexadecyl)oxy]-3-[[(9Z)-1-oxo-9-octadecen-1-yl]oxy]propoxy]phosphinyl]oxy]-N,N,N-trimethyl-, inner salt

Biological Activity

[Description]:

1-Oleoyl-2-palmitoyl-sn-glycero-3-PC derives from an oleic acid. 1-Oleoyl-2-palmitoyl-sn-glycero-3-PC can be used for the synthesis of liposomes[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Tomita T, et al. Influence of membrane fluidity on the assembly of Staphylococcus aureus alpha-toxin, a channel-forming protein, in liposome membrane. J Biol Chem. 1992;267(19):13391-13397.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₂H₈₂NO₈P

[ Molecular Weight ]:
760.076

[ Exact Mass ]:
759.577820

[ LogP ]:
11.42

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Barotropic and thermotropic bilayer phase behavior of positional isomers of unsaturated mixed-chain phosphatidylcholines.

Biochim. Biophys. Acta 1788(5) , 1056-63, (2009)

The bilayer phase transitions of six kinds of mixed-chain phosphatidylcholines (PCs) with an unsaturated acyl chain in the sn-1 or sn-2 position, 1-oleoyl-2-stearoyl- (OSPC), 1-stearoyl-2-oleoyl- (SOP...

Bridging the gap between molecular descriptors and mechanism: Cases studies by molecular dynamics simulations

J. Mol. Graph. Model. 27(7) , 829-35, (2009)

In recent years, both classification models and quantitative structure–activity relationships (QSARs) have been developed to discriminate the acute toxicity of polar narcotics and uncouplers. One of f...

The cytoplasmic region of mouse Fc gamma RIIb1, but not Fc gamma RIIb2, binds phospholipid membranes.

Biochemistry 38(7) , 2102-9, (1999)

The cytoplasmic regions of the mouse low-affinity Fc gamma RII isoforms, Fc gamma RIIb1 and Fc gamma RIIb2, play key roles in signal transduction by mediating different cellular functions. The Fc gamm...