9-Phenyl-9H-xanthen-9-ol

Names

[ CAS No. ]:
596-38-3

[ Name ]:
9-Phenyl-9H-xanthen-9-ol

[Synonym ]:
9-phenylxanthen-9-ol
EINECS 209-882-3
9H-Xanthen-9-ol, 9-phenyl-
9-Phenyl-9H-xanthen-9-ol
MFCD00005058

Biological Activity

[Description]:

Antioxidant agent-15 (Compound 4) is a potent antioxidant inhibition activity, with the IC50 of 15.44 nM. Antioxidant agent-15 inhibits tumor cell growth in Hela, Hep G2 and Caco-2 cells, with the IC50 of 395.26, 400.4 and 24.6 nM, respectively[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Immunology/Inflammation >> COX

[Target]

95.26, 400.4 and 24.6 nM (Hela、Hep G2 and Caco-2 cells)[1]

[References]

[1]. Abualhasan M, et al. Biological Evaluation of Xanthene and Thioxanthene Derivatives as Antioxidant, Anticancer, and COX Inhibitors. ACS Omega. 2023;8(41):38597-38606.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
432.6±24.0 °C at 760 mmHg

[ Melting Point ]:
158-161 °C(lit.)

[ Molecular Formula ]:
C₁₉H₁₄O₂

[ Molecular Weight ]:
274.313

[ Flash Point ]:
199.7±17.1 °C

[ Exact Mass ]:
274.099365

[ PSA ]:
29.46000

[ LogP ]:
3.60

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.674

MSDS

Click to get detail MSDS

Safety Information

[ Safety Phrases ]:
S22-S24/25

[ WGK Germany ]:
3

[ HS Code ]:
2932999099

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2932999099

[ Summary ]:
2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%