L-Glutamine-15N-1

Names

[ Name ]:
L-Glutamine-15N-1

[Synonym ]:
g-Glutamine
Glutamine, DL-
(2S)-2-amino-5-azanyl-5-oxopentanoic acid
MFCD00084214
Glutamine (VAN)
(±)-Glutamine
Gln
glutamine
UNII:5L555N1902

Biological Activity

[Description]:

L-Glutamine-15N-1 (L-Glutamic acid 5-amide-15N-1) is the 15N-labeled L-Glutamine. L-Glutamine (L-Glutamic acid 5-amide) is a non-essential amino acid present abundantly throughout the body and involved in many metabolic processes. L-Glutamine provides a source of carbons for oxidation in some cells[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Ferroptosis

Signaling Pathways >> GPCR/G Protein >> mGluR

Research Areas >> Metabolic Disease

[In Vitro]

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

[References]

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
445.6±40.0 °C at 760 mmHg

[ Melting Point ]:
185ºC (dec.)(lit.)

[ Molecular Formula ]:
C₅H₁₀N₁₅NO₃

[ Molecular Weight ]:
146.145

[ Flash Point ]:
223.3±27.3 °C

[ Exact Mass ]:
146.069138

[ PSA ]:
106.41000

[ LogP ]:
-1.67

[ Vapour Pressure ]:
0.0±2.3 mmHg at 25°C

[ Index of Refraction ]:
1.524

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3