6,7-Isoquinolinediol,1,2,3,4-tetrahydro-1-methyl-, hydrobromide (1:1)

Names

[ CAS No. ]:
59709-57-8

[ Name ]:
6,7-Isoquinolinediol,1,2,3,4-tetrahydro-1-methyl-, hydrobromide (1:1)

[Synonym ]:
1-methyl-1,2,3,4-tetrahydroisoquinoline-6,7-diol,hydrobromide
MFCD00012741

Chemical & Physical Properties

[ Boiling Point ]:
362.6ºC at 760 mmHg

[ Melting Point ]:
186-187ºC(lit.)

[ Molecular Formula ]:
C₁₀H₁₄BrNO₂

[ Molecular Weight ]:
260.12800

[ Flash Point ]:
175.4ºC

[ Exact Mass ]:
259.02100

[ PSA ]:
52.49000

[ LogP ]:
2.59140

[ Appearance of Characters ]:
white to brown

[ Storage condition ]:
Hygroscopic, -20?C Freezer, Under Inert Atmosphere

[ Stability ]:
Store in freezer at -20°C

[ Water Solubility ]:
H2O: soluble5mg/mL (warmed; clear solution)

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
R34

[ Safety Phrases ]:
S25-S36/37/39-S45

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2933499090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933499090

[ Summary ]:
2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Articles

A trivalent approach for determining in vitro toxicology: Examination of oxime K027.

J. Appl. Toxicol. 35(2) , 219-27, (2014)

Unforeseen toxic effects contribute to compound attrition during preclinical evaluation and clinical trials. Consequently, there is a need to correlate in vitro toxicity to in vivo and clinical outcom...