2-Methoxy-5-methylphenyl isocyanate

Names

[ CAS No. ]:
59741-04-7

[ Name ]:
2-Methoxy-5-methylphenyl isocyanate

[Synonym ]:
2-isocyanato-1-methoxy-4-methylbenzene
MFCD00013869

Chemical & Physical Properties

[ Density]:
1.112 g/mL at 25 °C(lit.)

[ Boiling Point ]:
240 °C(lit.)

[ Melting Point ]:
25-26 °C(lit.)

[ Molecular Formula ]:
C₉H₉NO₂

[ Molecular Weight ]:
163.17300

[ Flash Point ]:
>230 °F

[ Exact Mass ]:
163.06300

[ PSA ]:
38.66000

[ LogP ]:
1.97090

[ Index of Refraction ]:
n20/D 1.537(lit.)

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H302-H312-H315-H319-H332-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xn,Xi

[ Risk Phrases ]:
R20/22;R36/37/38;R42

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
2206

[ WGK Germany ]:
3

[ Packaging Group ]:
III

[ Hazard Class ]:
6.1

[ HS Code ]:
2929109000

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2929109000

[ Summary ]:
2929109000. other isocyanates. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

New N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs as sigma2 receptor ligands: synthesis, in vitro characterization, and evaluation as PET imaging and chemosensitization agents.

Bioorg. Med. Chem. 17(3) , 1222-31, (2009)

A series of N-substituted 9-azabicyclo[3.3.1]nonan-3alpha-yl phenylcarbamate analogs were synthesized. Among them, WC-26 and WC-59 were identified as the most potent sigma(2) receptor ligands (K(i)=2....