FQI1

Names

[ Name ]:
FQI1

[Synonym ]:
8-(2-chloro-benzoyloxy)-7-nitro-quinoline
o-Chlorobenzoic acid 7-nitro-8-quinolyl ester
8-(2-ethoxyphenyl)-7,8-dihydro-[1,3]dioxolo[4,5-g]quinolin-6(5H)-one
BENZOIC ACID,o-CHLORO-,7-NITRO-8-QUINOLYL ESTER
8-Quinolinol,7-nitro-,o-chlorobenzoate
7-nitroquinolin-8-yl 2-chlorobenzoate
FQI1

Biological Activity

[Description]:

FQI1 is a Late SV40 Factor (LSF) inhibitor. FQI1 inhibits cell proliferation, with IC50s of 3, 0.79, 6.3 μM for NIH/3T3, HeLa, A549 cells. FQI1 can be used for cancer research[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Ulla Hansen, et al. Inhibitors of late sv40 factor (lsf) as cancer chemotherapeutics. WO2012050985.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₇NO₄

[ Molecular Weight ]:
311.33

[ Exact Mass ]:
311.11600

[ PSA ]:
60.28000

[ LogP ]:
3.37320

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS06, GHS09

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H301-H400

[ Precautionary Statements ]:
P273-P301 + P310

[ RIDADR ]:
UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., HI: all