Dithizone
Names
[ CAS No. ]:
60-10-6
[ Name ]:
Dithizone
[Synonym ]:
(E)-N',2-Diphenyldiazenecarbothiohydrazide
Methanethione, [(E)-2-phenyldiazenyl](2-phenylhydrazinyl)-
Dithizone
Phenyldiazenecarbothioic Acid 2-Phenylhydrazide
MFCD00003025
diphenylthiocarbazone
EINECS 200-454-1
Biological Activity
[Description]:
[Related Catalog]:
Chemical & Physical Properties
[ Density]:
1.2±0.1 g/cm3
[ Boiling Point ]:
376.1±25.0 °C at 760 mmHg
[ Melting Point ]:
168°C (dec.)
[ Molecular Formula ]:
C13H12N4S
[ Molecular Weight ]:
256.33
[ Flash Point ]:
181.2±23.2 °C
[ Exact Mass ]:
256.078278
[ PSA ]:
80.87000
[ LogP ]:
4.01
[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C
[ Index of Refraction ]:
1.644
[ Stability ]:
Stable. Incompatible with strong oxidizing agents.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- LQ9450000
- CHEMICAL NAME :
- Formic acid, (phenylazo)thio-, 2-phenylhydrazide
- CAS REGISTRY NUMBER :
- 60-10-6
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 6
- MOLECULAR FORMULA :
- C13-H12-N4-S
- MOLECULAR WEIGHT :
- 256.35
- WISWESSER LINE NOTATION :
- RNUNYUS&MMR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,44,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 200 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NTIS** National Technical Information Service. (Springfield, VA 22161) Formerly U.S. Clearinghouse for Scientific & Technical Information. Volume(issue)/page/year: AD277-689
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 56 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#07955 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80827 No. of Facilities: 260 (estimated) No. of Industries: 7 No. of Occupations: 9 No. of Employees: 1195 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 80827 No. of Facilities: 69 (estimated) No. of Industries: 6 No. of Occupations: 7 No. of Employees: 2298 (estimated) No. of Female Employees: 1324 (estimated)
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S36-S26
[ RIDADR ]:
2811
[ RTECS ]:
LQ9450000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
Synthetic Route
Precursor & DownStream
Precursor
DownStream
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There is a clinical need for an alternative labeling agent for magnetic resonance imaging (MRI) in islet transplantation. We aimed to evaluate the feasibility of islet MRI using ferumoxytol, which is ...