5beta-Pregnan-20-one, 3alpha,11alpha-dihydroxy- (8CI)

Names

[ CAS No. ]:
600-52-2

[ Name ]:
5beta-Pregnan-20-one, 3alpha,11alpha-dihydroxy- (8CI)

[Synonym ]:
5BETA-PREGNAN-11BETA,17ALPHA,21-TRIOL-3,20-DIONE
11,17,21-trihydroxy-,(5beta,11beta)-pregnane-20-dione
dihydrocortisol
hydrocortison
5B-Dihydrocortisol
5B-pregnane-11B-17A-21-triol-3-20-dione

Chemical & Physical Properties

[ Density]:
1.117g/cm3

[ Boiling Point ]:
469.7ºC at 760 mmHg

[ Molecular Formula ]:
C₂₁H₃₄O₃

[ Molecular Weight ]:
334.49300

[ Flash Point ]:
252ºC

[ Exact Mass ]:
334.25100

[ PSA ]:
57.53000

[ LogP ]:
3.56600

[ Index of Refraction ]:
1.541

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: TU4381000

CHEMICAL NAME :: 5-beta-Pregnan-20-one, 3-alpha,11-alpha-dihydroxy-

CAS REGISTRY NUMBER :: 600-52-2

LAST UPDATED :: 199007

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C21-H34-O3

MOLECULAR WEIGHT :: 334.55

WISWESSER LINE NOTATION :: L E5 B666TJ A1 CQ E1 FV1 OQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 40 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 11,117,1968