Chlorobutanol hemihydrate
Names
[ CAS No. ]:
6001-64-5
[ Name ]:
Chlorobutanol hemihydrate
[Synonym ]:
1,1,1-Trichloro-2-methyl-2-propanol hemihydrate
1,1,1-Trichloro-2-methyl-2-propanol hydrate (2:1)
MFCD02179352
1,1,1-trichloro-2-methyl-2-propanol(hydrate) (2:1)
Chlorobutanol Hemihydrate
1,1,1-Trichloro-2-methylpropan-2-ol hydrate (2:1)
2-Propanol, 1,1,1-trichloro-2-methyl-, hydrate (2:1)
Biological Activity
[Description]:
[Related Catalog]:
[References]
Chemical & Physical Properties
[ Boiling Point ]:
167ºC
[ Melting Point ]:
75-79ºC
[ Molecular Formula ]:
C4H9Cl3O2
[ Molecular Weight ]:
372.929
[ Flash Point ]:
100ºC
[ Exact Mass ]:
369.923065
[ PSA ]:
29.46000
[ LogP ]:
2.06320
[ Appearance of Characters ]:
Crystalline Powder, Crystals and/or Chunks | White to almost white
[ Storage condition ]:
-20°C
[ Stability ]:
Stable. Generates toxic fumes on combustion. Incompatible with strong oxidizing agents.
[ Water Solubility ]:
Slightly soluble in water, very soluble in ethanol (96 per cent), soluble in glycerol (85 per cent). | Soluble in ethanol, ether, chloroform, and glycerol. Insoluble in water.
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302
[ Precautionary Statements ]:
P301 + P312 + P330
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R22;R36/37/38
[ Safety Phrases ]:
26-36/37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
UC0175000
Articles
J. Org. Chem. 70(21) , 8560-3, (2005)
A practical synthesis of benzisoxazole 1 and its conversion to alpha-aryloxyisobutyric acid 2 using 1,1,1-trichloro-2-methyl-2-propanol (chloretone) was developed. Benzisoxazole 1 was formed in high y...
Application of a capillary electrophoresis method for simultaneous determination of preservatives in pharmaceutical formulations.J. Sep. Sci. 28(2) , 137-43, (2005)
Preservatives are used to protect pharmaceutical formulations from microbial attack during the period of administration to the patient. Because of their biological activity, preservatives have to be i...
Freeze-drying above room temperature.J. Pharm. Sci. 88(5) , 501-6, (1999)
This study investigates the use of solid, organic compounds to lyophilize drugs without conventional freeze-drying equipment. The aim of the investigation is to find a pharmaceutically acceptable solv...