D-threo Sphinganine (d18:0)

Names

[ Name ]:
D-threo Sphinganine (d18:0)

Biological Activity

[Description]:

D-threo-Dihydrosphingosine is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Chemical & Physical Properties

[ Density]:
0.927g/cm3

[ Boiling Point ]:
446.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₈H₃₉NO₂

[ Molecular Weight ]:
301.50800

[ Flash Point ]:
223.7ºC

[ Exact Mass ]:
301.29800

[ PSA ]:
66.48000

[ LogP ]:
4.84850

[ Index of Refraction ]:
1.477

MSDS

Click to get detail MSDS

Safety Information

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Early and late HIV-1 membrane fusion events are impaired by sphinganine lipidated peptides that target the fusion site.

Biochem. J. 461(2) , 213-22, (2014)

Lipid-conjugated peptides have advanced the understanding of membrane protein functions and the roles of lipids in the membrane milieu. These lipopeptides modulate various biological systems such as v...

Myriocin, an inhibitor of serine palmitoyl transferase, impairs the uptake of transferrin and low-density lipoprotein in mammalian cells.

Arch. Biochem. Biophys. 526(1) , 60-8, (2012)

The role of sphingolipids in clathrin-mediated endocytosis is only poorly understood in mammalian cells. Thus the relationship between sphingolipid de novo synthesis and clathrin-mediated endocytosis ...

Terpene alcohols inhibit de novo sphingolipid biosynthesis.

Planta Med. 78(5) , 434-9, (2012)

The terpene alcohols geranyllinalool, phytol (diterpene alcohol), and farnesol (sesquiterpene alcohol) were newly found to inhibit sphingolipid de novo biosynthesis in LLC-PK₁ cells (pig kidney epithe...