CHOLESTERYL LINOLEATE

Names

[ CAS No. ]:
604-33-1

[ Name ]:
CHOLESTERYL LINOLEATE

[Synonym ]:
Cholesterol Linoleate
(8ξ,9ξ,14ξ)-Cholest-5-en-3-yl (9Z,12Z)-9,12-octadecadienoate
Cholesteryl linoleate
EINECS 210-065-9
9,12-Octadecadienoic acid, (8ξ,9ξ,14ξ)-cholest-5-en-3-yl ester, (9Z,12Z)-
MFCD00003644

Biological Activity

[Description]:

Cholesteryl linoleate is shown to be the major cholesteryl ester contained in LDL and atherosclerotic lesions.

[Related Catalog]:

Research Areas >> Metabolic Disease

Natural Products >> Others

[Target]

Human Endogenous Metabolite

[References]

[1]. Huber J, et al. Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway. Arterioscler Thromb Vasc Biol. 2002 Apr 1;22(4):581-6.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
677.3±44.0 °C at 760 mmHg

[ Melting Point ]:
42ºC

[ Molecular Formula ]:
C₄₅H₇₆O₂

[ Molecular Weight ]:
649.084

[ Flash Point ]:
364.0±16.0 °C

[ Exact Mass ]:
648.584534

[ PSA ]:
26.30000

[ LogP ]:
18.17

[ Vapour Pressure ]:
0.0±2.1 mmHg at 25°C

[ Index of Refraction ]:
1.517

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Autophagy facilitates secretion and protects against degeneration of the Harderian gland.

Autophagy 11(2) , 298-313, (2015)

The epithelial derived Harderian gland consists of 2 types of secretory cells. The more numerous type A cells are responsible for the secretion of lipid droplets, while type B cells produce dark granu...

A rapid and precise method for quantification of fatty acids in human serum cholesteryl esters by liquid chromatography and tandem mass spectrometry.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 960 , 222-9, (2014)

We described a rapid and precise method for simultaneous quantification of eleven fatty acids in human serum cholesteryl esters (CEFAs) by liquid chromatography and tandem mass spectrometry (LC-MS/MS)...

Oxidized cholesteryl linoleates stimulate endothelial cells to bind monocytes via the extracellular signal-regulated kinase 1/2 pathway.

Arterioscler. Thromb. Vasc. Biol. 22(4) , 581-6, (2002)

Oxidation products of cholesteryl esters have been shown to be present in oxidized low density lipoprotein and in atherosclerotic lesions. Monocyte adhesion to the endothelium is an initiating crucial...