GSK215083

Names

[ Name ]:
GSK215083

[Synonym ]:
unii-8gfe8j4n0z

Biological Activity

[Description]:

GSK215083 is a high affinity 5-HT6 receptor antagonist. GSK215083 can serves as a promising 5-HT6 radioligand candidate by radiolabeled with (11)C via methylation[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> GPCR/G Protein >> 5-HT Receptor

Signaling Pathways >> Neuronal Signaling >> 5-HT Receptor

[Target]

5-HT6 Receptor

[References]

[1]. Parker CA, et al. Radiosynthesis and characterization of 11C-GSK215083 as a PET radioligand for the 5-HT6 receptor. J Nucl Med. 2012 Feb;53(2):295-303.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₀FN₃O₂S

[ Molecular Weight ]:
385.46

[ Exact Mass ]:
385.12600

[ PSA ]:
61.89000

[ LogP ]:
4.04220