Pactimibe sulfate
Names
[ CAS No. ]:
608510-47-0
[ Name ]:
Pactimibe sulfate
[Synonym ]:
1H-Indole-5-acetic acid,7-((2,2-dimethyl-1-oxopropyl)amino)-2,3-dihydro-4,6-dimethyl-1-octyl-,sulfate (2:1)
CS-505
Pactimibe sulfate
UNII-FX3YKK43YM
Biological Activity
[Description]:
[Related Catalog]:
[Target]
ACAT1:4.9 μM (IC50)
ACAT2:3.0 μM (IC50)
ACAT:2 μM (IC50, in the liver)
ACAT:2.7 μM (IC50, in macrophages)
ACAT:4.7 μM (IC50, in THP-1 cells)
oleoyl-CoA:5.6 μM (Ki)
cholesteryl ester formation:6.7 μM (IC50)
[In Vitro]
[In Vivo]
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C50H82N4O10S
[ Molecular Weight ]:
931.27200
[ Exact Mass ]:
930.57500
[ PSA ]:
229.24000
[ LogP ]:
13.13320
Safety Information
[ Hazard Codes ]:
Xi